Fanconi Anemia (FA) (Stress Cytogenetics)
ITEM ID
XX025
Item Name
ABL1 TYROSINE KINASE DOMAIN MUTATION ANALYSISS
DOCTOR SPECIALITY
Hematologist
DISEASE DESCRIPTION
Genetics
Test Status
Active
Fanconi Anemia (FA) (Stress Cytogenetics)
Specimen
5 mL (3 mL min.) Whole blood from 1 Green Top (Sodium Heparin) tube. Ship at 18-22°C. DO NOT FREEZE. Give brief clinical history.
Method:
Stress Cytogenetics
Report:
Sample submitted by 2nd day of the month. Report issued in 4 weeks.
Usage:
Chromosomes from a patient with a congenital form of bone marrow failure, Fanconi''s anemia (FA), are sensitive to clastogenic agents (chemicals causing DNA breakage) like Mitomycin C (MMC). The effect of MMC on lymphocytes in culture is used to differentiate reliably between FA patients with chromosome instability and Idiopathic aplastic anemia.
Doctor Specialty:
Hematologist
Disease:
Genetics
Components::
Department:
CYTOGENETICS
Pre Test Information:
Give brief clinical history.